diff --git a/pyproject.toml b/pyproject.toml
new file mode 100644
index 00000000..02510847
--- /dev/null
+++ b/pyproject.toml
@@ -0,0 +1,42 @@
+[project]
+name = "research-stack"
+version = "0.1.0"
+description = "Research Stack — formally verified compute fabric"
+requires-python = ">=3.10"
+optional-dependencies = {
+  quantum = [
+    "perceval-quandela>=1.2.3",
+    "quimb>=1.4.0",
+    "opt_einsum>=3.3.0",
+    "cirq>=1.3.0",
+    "qiskit>=1.0.0",
+    "qiskit-aer>=0.14.0",
+  ],
+  gpu = [
+    "wgpu>=0.19.0",
+  ],
+  compute = [
+    "ray>=2.9.0",
+    "networkx>=3.1",
+    "scipy>=1.11.0",
+    "numpy>=1.24.0",
+  ],
+  db = [
+    "psycopg2-binary>=2.9.0",
+    "boto3>=1.28.0",
+    "gremlinpython>=3.7.0",
+    "pymysql>=1.1.0",
+  ],
+  pipeline = [
+    "reedsolo>=1.7.0",
+    "cryptography>=41.0.0",
+    "highspy>=1.7.0",
+    "requests>=2.31.0",
+    "pandas>=2.0.0",
+    "xxhash>=3.4.0",
+    "pyserial>=3.5",
+  ],
+  all = [
+    "research-stack[quantum,gpu,compute,db,pipeline]",
+  ],
+}
diff --git a/requirements.txt b/requirements.txt
new file mode 100644
index 00000000..f50d377c
--- /dev/null
+++ b/requirements.txt
@@ -0,0 +1,48 @@
+# Research Stack — Python dependencies
+# Install: pip install -r requirements.txt
+# Selective installs via pyproject.toml: pip install ".[quantum]"
+
+# Core numerical
+numpy>=1.24.0
+scipy>=1.11.0
+networkx>=3.1
+pandas>=2.0.0
+matplotlib>=3.7.0
+
+# Braid VCN Encoder Pipeline
+reedsolo>=1.7.0
+cryptography>=41.0.0
+
+# QUBO-to-MIP bridge (HiGHS solver)
+highspy>=1.7.0
+
+# AlphaProof loop (Ollama API)
+requests>=2.31.0
+
+# Photonic quantum simulation (Perceval SLOS)
+perceval-quandela>=1.2.3
+
+# Bosonic tensor networks
+quimb>=1.4.0
+opt_einsum>=3.3.0
+
+# QAOA adapter shims
+cirq>=1.3.0
+qiskit>=1.0.0
+qiskit-aer>=0.14.0
+
+# GPU compute
+wgpu>=0.19.0
+
+# Ray compute dispatch
+ray>=2.9.0
+
+# Data & serialization
+xxhash>=3.4.0
+pyserial>=3.5
+
+# Database backends
+psycopg2-binary>=2.9.0
+boto3>=1.28.0
+gremlinpython>=3.7.0
+pymysql>=1.1.0