* Spectral Encoder Circuit Simulation * Implements spectral encoding theory in analog circuit form * Based on Signal Theory Compendium spectral encoding theory * * Core concepts: * - Spectral signature: 8-bin amplitude vector * - Genetic event mapping to spectral peaks * - Spectral overlap and accumulation .title Spectral Encoder Analog Circuit Simulation * Input signals for genetic events (A, T, G, C) * Each event maps to a specific spectral bin VA_IN 2 0 PULSE(0 3.3 1n 1n 10n 20n 100n) VT_IN 3 0 PULSE(0 3.3 21n 1n 10n 20n 100n) VG_IN 4 0 PULSE(0 3.3 41n 1n 10n 20n 100n) VC_IN 5 0 PULSE(0 3.3 61n 1n 10n 20n 100n) * Spectral bin circuits (8 bins total) * Each bin is an RC integrator that accumulates charge * Bin 0 (Event A) R_BIN0 10 0 10k C_BIN0 10 0 10p E_BIN0 2 0 10 0 1 ; Voltage-controlled voltage source for event A * Bin 1 (Event T) R_BIN1 11 0 10k C_BIN1 11 0 10p E_BIN1 3 0 11 0 1 ; Voltage-controlled voltage source for event T * Bin 2 (Event G) R_BIN2 12 0 10k C_BIN2 12 0 10p E_BIN2 4 0 12 0 1 ; Voltage-controlled voltage source for event G * Bin 3 (Event C) R_BIN3 13 0 10k C_BIN3 13 0 10p E_BIN3 5 0 13 0 1 ; Voltage-controlled voltage source for event C * Remaining bins (4-7) - initially empty R_BIN4 14 0 10k C_BIN4 14 0 10p R_BIN5 15 0 10k C_BIN5 15 0 10p R_BIN6 16 0 10k C_BIN6 16 0 10p R_BIN7 17 0 10k C_BIN7 17 0 10p * Spectral overlap circuit (summing amplifier) * Computes inner product of spectral signatures R_SUM1 18 0 10k R_SUM2 19 0 10k R_SUM3 20 0 10k R_SUM4 21 0 10k E_SUM1 10 0 18 0 0.125 E_SUM2 11 0 19 0 0.125 E_SUM3 12 0 20 0 0.125 E_SUM4 13 0 21 0 0.125 R_SUM_OUT 22 0 2.5k E_SUM_OUT 18 21 22 0 1 * Output buffers for spectral bins E_OUT0 10 0 30 0 1 E_OUT1 11 0 31 0 1 E_OUT2 12 0 32 0 1 E_OUT3 13 0 33 0 1 E_OUT4 14 0 34 0 1 E_OUT5 15 0 35 0 1 E_OUT6 16 0 36 0 1 E_OUT7 17 0 37 0 1 * Analysis .TRAN 1n 200n .PLOT TRAN V(2) V(3) V(4) V(5) V(30) V(31) V(32) V(33) V(22) * Measurement commands .MEASURE TRAN bin0_peak MAX V(30) .MEASURE TRAN bin1_peak MAX V(31) .MEASURE TRAN bin2_peak MAX V(32) .MEASURE TRAN bin3_peak MAX V(33) .END